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07 January 2018
Photo Charl Devenish
Dr Anneke van der Spoel van Dijk is invested in contributing
to the global effort of stopping TB by 2035.
The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB).
She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB).
Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.
Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”
Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”
As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.
UFS praised for hosting international research development programme
2013-03-05
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At the farewell function were, from the left: Dr GansenPillay (deputy executive officer of the NRF), Emile Goofo (Cameroon), his son Tylio in the arms of Prof Nicky Morgan (Vice-Rector: Operations), Avelino Mondhane from Stockholm University (originally from Mozambique) and Prof Neil Heideman (Dean of the Faculty of Natural and Agricultural Sciences).
Photo: Leatitia Pienaar
05 March 2013 |
“I must congratulate the University of the Free State on doing something like this,” Dr Gansen Pillay said at the farewell function for the participants in the Southern African Young Scientists Summer Programme (SA-YSSP) at the UFS.
The 19 young scientists from 16 countries completed their three-month programme at the end of February 2013. As another step in the process the participants must write articles for reputable journals and complete their doctoral studies. Their performance in the research world will also be tracked.
Dr Pillay, deputy executive officer of the National Research Foundation (NRF), said an investment was made in the researchers to secure the future of the programme. A lot of persuasion and proof was necessary to convince the Austrian Institute for Applied Systems Analysis (IIASA) that a programme of this nature could be presented in Africa.
The SA-YSSP was hosted and managed by the UFS. The programme was developed by the NRF in collaboration with the Department of Science and Technology (DST) and IIASA into a novel and innovative initiative. The official launch was by the Minister of Science and Technology during November 2011.
The SA-YSSP will be an annual three-month education, academic training and research capacity-building programme. Aligned with the YSSP model, annually presented in Austria, the SA-YSSP offered scientific seminars covering themes in the social and natural sciences, often with policy dimensions, to broaden the participants’ perspectives and strengthen their analytical and modelling skills, further enriching a demanding academic and research programme.
Prof Martin Mtwaeaborwa, SA-YSSP deputy dean, said the academic performance of the young scientists superseded the expectations. “I hope the scholars will look back at the programme as the moment their careers began.”
The added, “The UFS received positive remarks for organising the programme and we hope to get it again in future.”