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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Fresh new look for UFS Sasol Library
2013-02-28

The revamped entrance area of the UFS Sasol Library.
14 March 2013
Photo: Johan Roux
The UFS Sasol Library on the Bloemfontein Campus has been given a new lease on life with a fresh new look to cater for the changing study needs of students. Over the last few months several upgrades have been made to ensure that students get an effective learning experience.

These upgrades will be spread over three phases. Upgrades include newly-built overnight study facilities, partitioned study areas for postgraduate students and areas for leisure reading. Special attention has also been given to security, with the access control system and the tattle-tape security system being moved to the foyer on Level 2. This level, which used to serve only as a thoroughfare to and from the eastern and western parts of the library, has been turned into proper foyers on either side.

"The UFS Library and Information Services are on a mission to present itself as the physical and virtual information hub of choice," says Director Betsy Eister.  "The increased intake of new students and technological developments has sparked the notion of new and revamped study spaces conducive to learning.”

Eister says that, after completion of all three phases, the library will have increased study spaces that appeal to different people with different needs – spaces for studying, leisure reading, newspaper reading, accessing wired and wireless connections and spaces for discussions.

The project which started in October 2012 is part of the university's space planning projects to optimally utilise space on the Bloemfontein Campus. The project will also see the Centre for Teaching and Learning move to level three of the library.

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