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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

World mourns giant of African literature
2013-03-25

 

UFS joins the world in commiserating the passing of the novelist, poet and literary critic, Chinua Achebe.
Photo credit: Mike Cohea/Brown University
25 March 2013

The staff and students of the University of the Free State (UFS) are saddened by the passing of Chinua Achebe on 21 March 2013 at the age of 82 in Boston in the United States.

Prof Achebe is widely regarded as one of Africa's greatest authors, gaining world-wide acclaim especially for his 1954 novel, Things Fall Apart. Prof Achebe’s other major works include Arrow of God, A Man of the People, Anthills of the Savannah, as well as his famous critique of Joseph Conrad's Heart of Darkness, namely An image of Africa: racism in Conrad's "Heart of darkness."

Prof Jonathan Jansen, Vice-Chancellor and Rector of the UFS, said he was privileged to attend three lectures by Achebe. "A giant in African literature has fallen. Go softly, Chinua Achebe. As a young student, I still remember sitting in awe of your wisdom and insight," he said.

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