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07 January 2018
Photo Charl Devenish
Dr Anneke van der Spoel van Dijk is invested in contributing
to the global effort of stopping TB by 2035.
The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB).
She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB).
Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.
Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”
Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”
As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.
Esteemed international Council advises the UFS
2013-03-26
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In front, from the left are: Prof Alice Pell, Vice-Provost for International Relations, Cornell University in the USA; Prof Jonathan Jansen, Vice-Chancellor and Rector of the UFS; Ms Jane Evans, Director of Ntataise Early Child Development Network Support Programme in South Africa; Mr Gert Grobler, Ambassador of South Africa to Madagascar and alumnus of the UFS. At the back, from the left are: Prof Joel Samoff, Professor in African Studies, Stanford University in the USA; Prof Teuns Verschoor, Vice-Rector: Institutional Affairs of the UFS; Prof Masafumi Nagao, Project Professor at the Graduate School for Frontier Sciences, University of Tokyo; and Prof Akilagpa Sawyerr, former Secretary General of the Association of African Universities (AAU), Ghana. Ms Phumzile Mlambo-Ngcuka, former Deputy President of South Africa, was absent when the photo was taken.
Photo: Sonia Small
27 March 2013 |
The International Advisory Council (IAC) of the University of the Free State (UFS) is visiting the Bloemfontein and Qwaqwa Campuses this week as part of its biennial meeting with the university leadership. The Council, consisting of seven leading academics, business leaders and policy makers, are advising the leadership on how well we perform against international benchmarks in research, teaching, service and transformation. The Council also acts as advocates for the university in their own spheres of influence.