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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Statement from Prof Jonathan Jansen regarding a misquote about Madiba
2013-04-10

08 April 2013

Comments made by learners who attended the Leadership Summit (pdf)

Prof Jonathan Jansen: Presentation about Great Leaders (pdf)

The news article that first appeared in Volksblad of Monday 8 April 2013 claiming that I wanted Madiba to die, refers.

This is a complete misrepresentation of what I said. My argument was that Madiba had done so much for South Africa, that he had served South Africa well, and that sometimes you just wish that people would leave him alone so that he can pass his final days quietly.

Like all South Africans, I want Madiba to live as long as possible, but without the constant glare and speculation of the media and others. He needs to be left alone to rest and die in peace. That was the content and context of what I said.

To misrepresent a lengthy statement on a talk which was entirely devoted to extolling Madiba’s leadership — alongside that of Luthuli, Ghandi and Martin Luther King Jr (this was the main photograph on the screen) — is mischievous. The seven characteristics of leadership of Mandela, and the other three, were what the one hour and ten minute talk was about — something completely ignored in the misrepresentation.

It is true that I depicted the crises from Marikana to the Catholic Church as crises of leadership and not primarily military or religious blunders.

It is also true that I argued that the official representation of the hospital visits as ‘routine checkups’ was inaccurate for aged people, since at the age of 94 no hospital visit is ‘routine.’ That is what I said.

- Prof Jonathan Jansen, Vice-Chancellor and Rector, University of the Free State

Media Release
08 April 2013
Issued by: Lacea Loader
Director: Strategic Communication
Tel: +27(0)51 401 2584
Cell: +27(0)83 645 2454
E-mail: news@ufs.ac.za

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