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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Students excel at National Championships for the Physically Disabled
2013-04-07

 

South African record-holder Danie Breitenbach (left) running with his guide at the 2013 Nedbank National Championships for the Physically Disabled.
Photo: Hetsie Veitch
10 April 2013

Six gold, one silver and two bronze medals. That is the number of medals students of the University of the Free State won at the 2013 Nedbank National Championships for the Physically Disabled, held in Pretoria. 

Louzanne Coetzee, Danie Breitenbach, Juanré Jenkinson and Diederich Kleynhans held the Kovsie flag high, winning medals in track and field events. Louzanne and Danie, both visually-impaired students, each won three gold medals, with Danie setting two new South African track records. Danie, who took part in the T11/F11 sports class for visually-impaired, totally blind athletes, set records in the 800 and 1 500 metre track events. This first-year BA student, who runs with a guide and has to wear a blindfold when running, also won a gold medal in the 400-metre track event. 
 
Louzanne also took part in the T11/F11 sports class and won gold medals in the 800-, 1 500- and 5 000-metre events. With her winning time of 2 minutes and 53,8 seconds in the 800 metres, Louzanne, a second-year BA Corporate and Marketing Communication student, reached the qualifying standard for international participation. She may be considered for a national team that will compete internationally. 
 
Diederich and Juanré took part in the F37 and F38 sports class for physically-impaired athletes and won medals in the field events. Juanré, a fourth-year Education student, and Diederich, a master’s degree Theology student, won bronze and silver medals in shotput. Diederich also won a bronze medal in discus. 
 
Also taking part in the national championships, were Sidwell Monyane, a final-year B Public Management (Human Resource Management) student. Sidwell was part of the Free State Boccia team. Boccia is a target-ball sport for athletes with disabilities, which has a major impact on motor skills.

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