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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS commemorates life and legacy of Bram Fischer
2013-04-26

 

26 April 2013
Photo: Stephen Collett

  • Speech - Bram Fischer Memorial Lecture (Pdf)

The university celebrated the life and legacy of the struggle icon Bram Fischer – the Kovsie Alumnus who helped shape the landscape of South African history. The university paid homage to the anti-apartheid stalwart on 26 April 2013, hosting the first Bram Fischer Memorial Lecture with well-known academic and human rights lawyer Prof Barney Pityana as the guest speaker. Prof Pityana was joined on the Bloemfontein Campus by Fischer’s daughters Ruth Rice and Ilse Wilson and his nephew Peter.

Early in the day, the Fischer sisters honoured their father’s legacy speaking at a critical conversation hosted by the Institute for Reconciliation and Social Justice. They later joined Prof Pityana in a discussion with students where Prof Pityana spoke about the history of the South African Students Organisation (SASO) and the role of student leaders.

In his memorial later in the evening, Prof Pityana highlighted Fischer’s contribution in the struggle for justice, notably his role as lawyer in the Rivonia trial. He gave a critical evaluation of South Africa’s legal system speaking at length about accessibility and transformation of the system.

In his thank you speech Prof Johan Henning, Dean of the Faculty of Law, reminded the audience of the prominent role the Fischer family played in the history of the UFS. Fischer’s father Adv Percy Fischer was the very first law academic and founder of the Faculty of Law at the Grey University College, now the UFS. One of his earliest students was CR Swart, the first LLB graduate at the UFS. Fittingly, the inaugural lecture was hosted in the CR Swart Building, home to the Faculty of Law.

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