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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Transformation in higher education discussed at colloquium
2013-05-16

16 May 2013

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The University of the Free State hosted the Higher Education Transformation Colloquium earlier this month on the Bloemfontein Campus.

On Monday 6 May 2013 till Wednesday 8 May 2013 the event brought together a wide range of stakeholders, including some members of university councils; vice-chancellors; academics and researchers; leaders of student formations and presidents of student representative councils; transformation managers; executive directors with responsibility for transformation in various universities, members of the newly established Transformation Oversight Committee and senior representatives from the Department of Higher Education and Training.

The event examined and debated some of the latest research studies and practices on the topic, as well as selected case studies from a number of public universities in South Africa.

Delivering a presentation at the colloquium, Dr Lis Lange, Senior Director of the Directorate for Institutional Research and Academic Planning at the UFS, said transformation in South Africa has been oversimplified and reduced to numbers, and the factors that might accelerate or slow the process have not been taken into account.

Dr Lange was delivering a paper, titled: The knowledge(s) of transformation: an archaeological perspective.

Dr Lange argued that “in the process of translating evolving political arguments into policy making, the intellectual, political and moral elements that shaped the conceptualisation of transformation in the early 1990s in South Africa, were reduced and oversimplified.”

She said crucial aspects of this reduction were the elimination of paradox and contradiction in the concept; the establishment of one accepted register of what transformation was and it is becoming sector-specific or socially blind. This means that the process was narrowed down in the policy texts and in the corresponding implementation strategies to the transformation of higher education, the schools system, the judiciary and the media, without keeping an eye on the structural conditions that can influence it in one way or another.

Dr Lange said the need for accountability further helped with reduction of transformation. “Because government and social institutions are accountable for their promises, transformation had to be measured and demonstrated.”

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