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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS Celebrates Africa Day
2013-05-24

 

At the Africa Day Memorial lecture was, in front from left: Dr Choice Makhetha, Vice-Rector: External Relations; Prof Henning Melber and Prof Heidi Hudson, Head of the Centre for Africa Studies. At the back is Prof Lucius Botes, Dean of the Faculty of the Humanities.
Photo: Stephen Collett
24 May 2013


Prof Henning Melber: Lecture (pdf)

The University celebrated the 50th anniversary of Africa Day by hosting the annual Africa Day Memorial lecture. Hosted by the Centre for Africa Studies (CAS), celebrations included a day-long colloquium which looked at the continent from various disciplines.

Delivering the Africa Day and also his inaugural lecture, Prof Henning Melber, Extraordinary Professor at CAS, spoke about the mystifying power of ideology and identity with regard to Africa and Africa (n) studies.

Before his lecture, senior professors from different faculties took part in a colloquium, delivering papers on a variety of topics relevant to the continent. In a session on historical-political legacies, Prof Hussein Solomon, Senior Professor in the Department of Political Science, spoke about Critical Terrorism Studies and its implications for Africa. He was joined by Prof Jo van As, Head of the Department of Zoology and Entomology, who spoke about the legacy of colonialism on the conservation of Africa’s river systems. Others topics which were addressed, included the development of sign language, cardiac medicine and science and mathematics education in Africa.

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