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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

"Growing Vegetables"-video to help communities
2005-11-28

The Centre for Agricultural Management at the University of the Free State (UFS) handed a copy of a video on how to start a vegetable garden, Growing Vegetables, to Mr Casca Mokitlane, MEC for agriculture in the Free State.  The video was made by the centre and First National Bank (FNB) and demonstrates step by step how to plan a vegetable garden, how to lay it out and how to sell the vegetables.  Copies of the video will be distributed to poor schools and other people/organisations in the Free State who are involved in community development.

During the launch of the video and accompanying brochure at the centre of the Mangaung University of the Free State Community Partnership Project (MUCPP) special recognition was given to Mrs Dora du Plessis (from the UFS Centre for Agricultural Management and coordinator of the project) for the more than 2000 hours of overtime she put into the making of the video.  From the left are Mr Sieg Maier (Provincial Manager of FNB), Mrs du Plessis and Dr Wimpie Nell (Director of the UFS Centre for Agricultural Management). Photo: Leonie Bolleurs

 

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