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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Board of Directors of the International Institute for Development and Ethics
2006-03-17

During the recent meeting of the Board of Directors of the International Institute for Development and Ethics (IIDE), office bearers were elected and approval was granted for its conversion into a Section 21 Company.  The IIDE specialises in the studying and research of general questions of developmental theory and practices and provides services and support in education, strategic planning, policy formulation, advocacy and capacity building of development agencies.  The office of the IIDE in Africa is situated on the Main Campus of the UFS in Bloemfontein.  The UFS is a funder of the IIDE together with the Paul Foundation and private sponsors from the Netherlands.

 

The IIDE in Africa's Board of Directors are from the left Mr Willem Ellis (newly elected executive officer of the IIDE) and Prof Annette Combrink (Deputy Chairperson of the IIDE in Africa and Rector of the North West University's campus in Potchefstroom). At the back from the left are Prof Lucius Botes (Director: Centre for Development Support at the UFS), Rev Kiepie Jaftha (Chairperson of the IIDE in Africa and Chief Director:  Community Service at the UFS), Prof Sytse Strijbos (IIDE Europe and affiliated to the University of Amsterdam),  Dr Amon Kasambala (Director: Focus on the Family, Africa) and Rev Tshililo Liphadzi (Reformed Church    Chiawelo in Soweto).

Photo: Lacea Loader

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