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07 January 2018
Photo Charl Devenish
The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB).
She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB).
Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.
Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”
Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”
As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.
Colloquium on legal ethics
2006-03-22
The Department of Constitutional Law and Philosophy of Law at the University of the Free State (UFS) presented a colloquium on legal ethics. The topic was The churches and the legality of abortion in South Africa.
Some of the speakers at the colloquium were front from the left Cardinal Wilfrid Napier (Head: Roman Catholic Church in South Africa), Mr Jeffery Ventrella Esq (guest speaker and Deputy Director, Alliance Defence Fund, United States of America) and Mrs Miranda Pillay (representative of the Anglican Church of South Africa and from the Faculty of Theology at the University of the Western Cape). In the middle from the left were Dr Michiel du Rand (General Surgeon, School of Medicine, University of Pretoria), Ms Jeanine McGill (Abortion Activist and Secretary of the ACDP, Western Cape), Prof Etienne de Villiers (representative of the Dutch Reformed Church and from the Faculty of Theology at the University of Pretoria) and Prof Jakobus Vorster (Dean: Faculty of Theology, University of the North West). Back from the left were Mr Shaun de Freitas (organiser of the colloquium and senior lecturer at the UFS Department of Constitutional Law and Philosophy of Law) and Mr John Smyth QC (legal representative of 'Doctors for Life', South Africa).
Photo: Stephen Collett