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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Another L’Atelier feather in the university’s cap
2013-07-24

 

Pauline Gutter, winner of this year’s Absa L’Atelier competition
Photo: Supplied
23 July 2013

"Dagbreek: Die Dagbreker" - interview with Pauline Gutter (YouTube)

A former Kovsie won the Absa L’Atelier competition – South Africa’s most prestigious art competition – for the second year in a row.

Pauline Gutter, who completed her BA Fine Arts degree at the UFS in 2003, is the second artist from the Free State to win the competition, which is in its 28th year of existence. In 2012, Elrie Joubert, another former Kovsie student from the Department of Fine Arts, won the competition as well.

As overall winner, Gutter receives a cash prize of R125 000 and six months’ residency in the studio apartment Cité Internationale des Arts in Paris, France.

Her winning entry, Die huweliksaansoek, is an interactive work consisting of a 1.8 m high association-rich obelisk, an engraved plaque, a small TV monitor and a farm-line handset. A video of a bull standing in a crush while semen is being drawn from it, is displayed. The viewer is invited to listen in voyeuristically. The soundtrack for the text is composed of statements and comments made by participants in the programme “Boer soek `n Vrou”. The question highlighted by the work, is, “does a farmer choose his future wife in the same way he breeds his stud animals?”

Pauline says her association with the farm, principled parents and strong family ties serve as inspiration for her work. To express her artistic voice in a contemporary environment is to be a close observer of society, she says. “It’s to ask questions which confront the viewer in a provocative way.”

Her advice to new artists is “hard work, sustainability and commitment. Keep looking until you find the place where you fit in.”

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