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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

University publishes its Integrated Report
2013-08-23

23 August 2013

The university is proud to have published an integrated report in line with the King III requirements on corporate governance. The university is one of the first universities – if not the first – in South Africa to do so. The UFS sees integrated reporting as a public process through which we report to all our stakeholders, using evidence-based data, on the achievements and challenges of a public university.

Our first Integrated Report reviews the overall performance, non-financial and financial, of the UFS for the 2012 academic year. It is the first report of its kind delivered to stakeholders and guided by the King III framework which recommends integrated, sustainable performance that is reported in a way that enables stakeholders to make an informed assessment of an institution.

The Integrated Report notes that the conditions under which higher education institutions operate have become more demanding in the last two decades and there is a growing need for universities to be more explicit and transparent about the manner in which their core functions (teaching, research and public duty), as well as its administrative operations, are defined by and support good governance, sustainability and corporate citizenship.

The university welcomes this opportunity to present in public an integrated account of itself. In particular, the UFS sees this report as an opportunity to align more strongly its financial and non-financial reporting in pursuit of organisational sustainability and social transformation in South Africa.

Prof Jonathan Jansen, Vice-Chancellor and Rector, notes in the report that in the past four years the university has made significant progress in respect of its two foundational commitments, the Academic Project and the Human Project.

There are now more students entering the university who satisfy the higher requirements set for admission. “This will improve the throughput and graduation rates of incoming students, ensuring their personal success and satisfaction with higher education.” The establishment of a state-of-the-art Postgraduate School, for example, is expected to increase the number, quality and success rates of postgraduate students.

The research output has increased steadily and the contribution of the new Senior Professors project, as well as the five research clusters, have helped to improve the quality of research and the spread of postgraduate recruitment beyond South Africa.

On transformation, the Vice-Chancellor observes that “We have made significant progress in building inclusive, democratic and embracing campus cultures which affirm the value and dignity of all students and staff. With the steady increase of black students in a majority black campus, our goal remains to retain our diversity in a university that serves as an experiment in teaching students to live and learn and love together.”

Financial sustainability is a major commitment and the UFS has not only maintained its record of unqualified audits, but has steadily built a culture of risk management and performance evaluation throughout the system. Internal auditing is a strong instrument in our arsenal to secure financial and operational compliance in every department of the university.

“What integrates the systems and functions of the university is the alignment of everything we do with our two pillars, the Academic and Human Projects, built on a solid foundation of professional support services as described in the Strategic Plan adopted in 2012. In the process of preparing the Integrated Report we discovered how much still needs to be done to align the still disparate and independent activities of the three campuses, seven faculties and more than 100 departments of this large university,” according to the Vice-Chancellor.

The report is available at: http://www.ufs.ac.za/content.aspx?id=184.

 

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