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07 January 2018
Photo Charl Devenish
Dr Anneke van der Spoel van Dijk is invested in contributing
to the global effort of stopping TB by 2035.
The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB).
She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB).
Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.
Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”
Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”
As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.
Pat Fahrenfort throws a spanner in the works
2013-08-24
23 August 2013
Pat Fahrenfort had the audience in stiches while discussing her book, Spanner in the Work: One Woman’s Journey from Factory Floor to Corridors of Power. In addition to her wit being razor-sharp, so was her insight.
The author narrated her winding journey from cold factory floors to the passages of parliament during an event hosted by Prof Jonathan Jansen, Vice-Chancellor and Rector, at the Institute for Reconciliation and Social Justice. Fahrenfort left school at the age of 15 and started her employment as a factory worker in Cape Town. Through sheer strength of will, she completed a university degree later in her life and went on to work alongside some of our leading political figures and as part of South Africa’s Constitutional Assembly.
Fahrenfort imparted her struggles in the workplace for democracy, justice and equality. Against this background, though, she expressed her disillusionment regarding some aspects of the current political environment in South Africa.
She also regaled the crowd with her ‘stalking’ tactics – back when she was still a fledgling writer – to grab the attention of author Antjie Krog. Fahrenfort attended quite a few functions where the famous author appeared – seemingly by chance – until she got her opportunity.The end result? Krog assisted Fahrenfort to write her own book. And the rest, as they say, is history.