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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Kovsies help SA Badminton win gold at 2013 AFCON
2013-08-27

 

Elmé de Villiers, Andries Malan, Wiaan Viljoen and Sandra le Grange.
Photo: Supplied
27 August 2013

A former Kovsie and the current captain of the South African Badminton team, Olympian Wiaan Viljoen, won two gold medals at the 2013 Africa Cup of Nations (AFCON) Individual events that concluded in Mauritius on 20 August 2013.

South Africa proved their dominance in the 2013 Continental Championships by winning three gold, two silver and three bronze medals in the Individual events. Combined with the gold medal for the team, South Africa won four out of the six gold medals up for contention, with the other two going to Mauritius in the ladies’ singles and to Seychelles in the ladies’ doubles respectively.

Kovsies’ Elmé de Villiers and Sandra le Grange also carried the ladies’ side of the South African team through every match of the AFCON and De Villiers won the deciding match in the final against Nigeria. De Villiers has been included in the 2016 Road to RIO BWF Project of Excellence. Both De Villiers and Le Grange are players to watch closely en route to the 2016 Olympic Games.

De Villiers and Le Grange also won the doubles title at the Mauritius International, which was held in the week after the AFCON. This was the first international title for both De Villiers and Le Grange.

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