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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Nkanyezi Talk @UFS looks at gender in the 21st century
2013-08-28

 
Lively debates and conversations as students discuss the topic of gender in the 21st century.
28 August 2013
Photo: Linda Fekisi

Students gathered at the CR Swart Senate Hall for the second Nkanyezi Talk @UFS dialogue session. Nkanyezi Talk @UFS is a student initiative that gives students a platform to voice their thoughts and ideas about issues affecting them during and after their university life.

The August-inspired topic, Gender in the 21st century, focused mainly on women. The talk looked at women in the workplace, the role that the media plays in redefining women and how South Africans can integrate the works of theorists on gender into their everyday lives.

A panel of guest speakers included Ace Moloi, former news editor of the Irawa student newspaper at the University of the Free State and News24 contributor, Leah Molatseli, an associate attorney at Phatshoane Henney Attorneys, and Bongi Tsoleli, who is the chairperson of a portfolio in the Free State Legislature.

“We need to take own initiative as students. We need to understand what they want, as well as the issues they are confronted with,” says Bongani Zwane, founder member of Nkanyezi Talk.

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