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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Arts and Social Justice festival brings creativity and academia together
2013-08-28

 

Photo: Linda Fekisi
14 August 2013



Who really benefited from the post-1994 democratic dispensation in the sports arena? What happened to the heroes of non-racial sport? Did the 1992 transition to unification wipe out an entire history of black sport in rugby and replaced it with a sanitized version of the sport?

These are some of the questions film producer Mark Fredericks explores in his thought-provoking documentary film ‘Injury Time’. The film is one of several documentaries screened as part of the second annual Artistic and Social Justice Week, hosted by the Institute for Reconciliation and Social Justice from 19 to 31 August 2013.

Extended from last year's one-week run, this year’s programme is packed with great productions, exhibitions and intellectual encounters celebrating freedom of expression. A highly-anticipated event on the programme is the open-air film screening of the documentary 'Dear Mandela' on Friday 30 August. This film follows the journey of three young people from their shacks to the highest court in the country as they invoke Nelson Mandela's example and become leaders in a growing social movement.

Speaking at the opening of the festival, Prof André Keet, Director of the Institute, said the purpose of the two week programme is to explore new and different ways of understanding social relations. "It’s an endeavour which is crucial to the Institute's objective of confronting the histories, policies and practices that has shaped and constrained the intellectual and social mandate of universities across the country and world."



“The role of art and literature in reflecting on society, has overtaken – in terms of substance, quality and relevance – the function of critical commentators, political analyst, sociologists and philosophers. Artists are, simply put, better political commentators than political commentators themselves. Better political commentators than philosophers, better political commentators than political analysts. Uniquely positioned to engage with social reality, art and literature demand that we experience artistic work as political acts.” Prof André Keet

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