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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Interior dome of Naval Hill planetarium reaches completion
2013-09-04

 

Work on the inside of the dome
Photo: Reinier Brönn
01 September 2013

The interior perforated aluminium planetarium dome has been installed by an American expert from Astro-Tec, the American company that customised the dome for the planetarium on Naval Hill. The planetarium, the first digital planetarium in sub-Saharan Africa, is scheduled to open in November 2013. The UFS manages the project.

The dome arrived in parts by ship from the USA in June 2013. These parts consisted of a number of long curved ‘ribs’ and numerous perforated panels. The panels were attached in sections to the ribs to form a smooth concave shell, creating the surface for the projection system.

The next step will be the installation of the projection system itself.

The 86-year old Lamont-Hussey Observatory on Naval Hill, also known as the Sterrewag Theatre, is home to the planetarium. The planetarium is the first component of a proposed Centre for Earth and Space. This will be a multi-purpose facility to promote science communication and preservation, and the arts.

This project is a long-term partnership between three main organisations, each bringing essential components to the project: the Mangaung Metro Municipality (MMM) as the land-owner, the Free State Department of Economic Development, Tourism and Environmental Affairs (DETEA) and the UFS, which developed the concept for the planetarium project and will be responsible for its operation and further fundraising endeavours.

The National Department of Science and Technology also joined this venture subsequent to providing substantial funding to the UFS in order to purchase the projection system for the planetarium.

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