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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Intervarsity 2013 a paragon of friendly rivalry
2013-08-06

 

Photo: RooistoelTv
10 August 2013

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The recent intervarsity between the University of the Free State (UFS) and the North-West University was a huge success. This 70th celebration of intervarsity between the two institutions, which took place for the first time in 1927, is the oldest event of its kind in South Africa.

According to Rudi Buys, Dean of Student Affairs at the UFS, it is also the most comprehensive and most innovative intervarsity in the country and since 2010 includes all incorporated campuses of universities such as the University of the North. The focus is no longer on sports only, but also on cultural programmes and forums for discussion between student leaders.

Of the 32 sport and culture activities intervarsities between the UFS and the NWU, the UFS won 16, the NWU 13 and three ended in a tie.

Sports and cultural activities like debate were held across the Bloemfontein Campus. Record numbers of supporters attended the different matches, debating competitions and festivities. The first SRC Presidents’ Reunion that took place during the intervarsity is regarded as a special milestone in the history of the UFS.

“We are particularly satisfied that students of diverse backgrounds and campuses took part in and attended intervarsity events and in this way showcased the rich variety of Kovsies with great pride,” Buys said.

“The successful course of the intervarsity confirms that it is important for the UFS to maintain its proud history of almost 100 years with the NWU, but to also update in order to reflect our young democracy and in pace with a young generation of South Africans who are now our students,” Buys concluded.

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