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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Appreciating student leaders in the Kovsie community
2013-09-06

 
Anesu Ruswa with the students from the Heimat Association at the appreciation ceremony.
6 September 2013
Photo: Damane Muzi Gwebu

Over 290 certificates were recently awarded to students by the Associations and Dialogue Office. The students received recognition for the crucial role that they play in student leadership.

This appreciation function was the brainchild of Anesu Ruswa, who is the former chairperson of the office. “I realised that the executive committees of various student associations do a lot for the general student community, with neither recognition nor recompense – so I decided to change that. The appreciation function was a first step in recognising associations as incubators of future leaders and hubs of the student-life experience,” he says.

Anesu, who has served in the associations’ office for two consecutive years, says that a highlight for him in the past year was the lessons of organisation and professionalism that he learnt from his administrative executive committee. “We set up systems and structures in the Associations’ office which, with all humility, no other portfolio can match.”

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