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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

University tips its hat to final-year students
2013-09-13

 
From the left: Lauren Marais, Werner Landman, Herloise Jordaan and Louis Rossouw (PwC).
13 September 2013

The Alumni Office at the University of the Free State (UFS), in partnership with PricewaterhouseCoopers (PwC), held its first Alumni Evening for final-year students.

The students received valuable advice from various speakers during the event. Werner Landman – also a UFS graduate – highlighted the differences in approach between the current and previous generations. Landman explained that Generation Y students have greater influence and are extensively connected socially as they enter the work environment. “You are people who will work to live, unlike us, Generation X, who live to work,” he said. With their degrees – some already busy with their post-graduate studies – they are more likely to be appointed in professions which will allow them to live better, he added.

Heloise Jordaan, former 2008/9 SRC president, who holds three degrees from Kovsies to her name, also addressed the final-years. She currently holds the position of brand manager at Urban Hotels, although she only started working recently. Through sharing her personal work experiences, she gave the audience a glimpse into the workplace."You guys need to realise that when you step into the working sphere, you need to be open minded and also work to the best of your abilities,” Jordaan encouraged.

The evening was concluded on a high note with a prize-giving. Pieter du Toit, UFS Alumni Chair, was in charge of handing over the awards. Residences were compared to find which ones generated the most residing final-year and postgraduate students. House Tswelopele and Soetdoring clinched the honours and walked away with R2 000 each for their house.

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