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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Supplementum analyses the San origin of South African place names
2013-09-25

 

At the launch were, from the left: Prof Lucius Botes (Dean: Faculty of the Humanities), Christine van Deventer (SUN MeDIA), Prof Peter Raper (author), Prof Theodorus du Plessis (Head of Department: Linguistics and Language Practice), and Prof Dirk van den Berg (outgoing editor).
Photo: Jerry Mokoroane
25 September 2013

The Acta Academica Supplementum 2012 (2), under the outgoing editorship of Prof Dirk van den Berg, was launched on 16 September 2013. The author, Prof Peter Raper, is one of the leading place-name experts in South Africa. The Supplementum analyses the San origin of South African place names whereby different layers of language contact are exposed. For example, Dipodi (previously Jakkalsdraai), is an adaptation of the original San name. The first ‘di’ is the added Sotho preposition. ‘Po’ is equal to the San word ‘po’ (jackal) and the last ‘di’ equal to ‘/gi’ (to bend). Prof Raper’s research indicates that many place names carry evidence of various language shifts. By analysing these language layers, different phases of language contact are exposed. This research is instrumental in the preservation of a unique aspect of the South African cultural heritage.

Prof Raper is since 2011 Honorary Professor: Linguistics, in the Department of Language Management and Language Practice at the University of the Free State. He is one of South Africa’s leading toponymists. The fourth edition of the New Dictionary of Southern African Place Names, with Dr Lucie Möller and Prof Theodorus du Plessis as co-editors, is currently in the press. He is a member of the Commission for Toponymy of the International Geographical Union, as well as the Working Group for Toponymy of the International Cartographic Association, of which there are only ten members worldwide, and a member of the Editorial Advisory Board for the journal Names.

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