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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

“Leisure can be of great geographical importance”
2013-09-26

 

Prof Gustav Etienne Visser
Photo: Supplied
26 September 2013
 

Prof Gustav Etienne Visser (43) is Professor in Human Geography at the University of the Free State. He has been with the university’s Geography Department since January 2002 and became a full professor in 2009.
Visser completed his MA in Geographical Research at the Stellenbosch University in 1996 and finished his PhD in Geography at the London School of Economics and Political Science in 2000. His thesis was titled: Spatialities of social justice: reflections on South African Cities.

Visser was a Post-doctoral Fellow at the School of Geography, Archaeology and Environmental Studies at the University of the Witwatersrand before his appointment at the UFS. He now teaches Urban Geography to third-year students and Tourism and Development to MA students.

His research interests so far have been Identity-based consumption and urban morphological change, Tourism and development nexus and Critical reflections on South African Geographical Research.

Visser’s publications summary is as follows:

- Four books – edited collections
- 28 book chapters
- 71 refereed articles
- Nine academic commentaries and research notes
- 14 research reports
- and 38 conference papers

His latest research on how people’s leisure time influences our urban spaces, is fundamentally relevant to everyday life.

“We tend to forget to think about it, but how people spend their leisure time is part of their lifestyle,” says Visser.“ And our urban surroundings are influenced by the lifestyles of its inhabitants.”

When asked about his own leisure time and activities, Visser humorously responds “There is no such thing.”

However, he is passionate about eating, cooking and wine.
“I must also watch a series every day – Dexter is definitely my favourite.
“Furthermore, I also travel abroad for about three months of the year, which is mainly for my research concerning urban spaces.”

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