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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Multitudes celebrate dr Beyers Naude's selfless life
2013-09-14

26 September 2013

The lecture was held in partnership with the diverse churches, the youth, the house of traditional leadership. The theme was Love for Humanity.

In his special message to the gathered religious leaders, students and staff, Apostle Saki Thapong, challenged all in attendance to “look for your own miracles within yourself.”

“We need a generation of miracles and not a generation of people running after miracles”, said Apostle Thapong.

“Allow your miracle to manifest itself within you and never look at your own miracle through your own time, but through God's time and purpose”, Pastor Thapong said.

In focusing on the choice of the theme, Vice-Rector: External Affairs, Dr Choice Makhetha, said that the theme was very important to all stakeholders who needed to pledge their commitment to building a community of people who care deeply about the safety of its children and senior citizens.

“As stakeholders in the Thabo Mofutsanyana District Municipality, we need to collectively build a society courageous enough to dirty its hands to shape the socio-economic development of this area, for the benefit of the local people, the country and the world. We must build a community of people who work tirelessly to ensure that the dignity of every human being is restored and protected, especially women,” said Dr Makhetha.

Previous speakers in the series include, Dr Allan Boesak, Prof Kwandiwe Kondlo, Dr Frank Chikane, Mr Johann Naude (Dr Naude's son) and Prof Jonathan Jansen.

Dr Beyers Naude was an ordained minister in the Dutch Reformed Church who stood against apartheid despite his advantaged Afrikaner background. In the aftermath of the Sharpeville Massacre of March 1960, 'Oom Bey' started questioning the morality of the government's policies. At the time of his passing away in September 2004, he was described as a “true humanitarian and true son of Africa” by Nelson Mandela.

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