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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

More international recognition for Vice-Chancellor
2013-09-27

27 September 2013

Two international awards will be bestowed on Prof Jonathan Jansen, Vice-Chancellor and Rector of the University of the Free State (UFS), in the coming months for his dedication to Education.

These awards will add to the multiple international and local achievements and awards Prof Jansen has received this year.

He will join the ranks of laureates of Kappa Delta Pi (KDP) during the organisation’s 49th Biennial Conference in Dallas, Texas, from 24 to 26 October 2013. KDP is an international honour society in education, founded by Dr William Bagley at the University of Illinois in 1911. It was established to foster excellence in education and promote fellowship among those dedicated to teaching. KDP comprises 600 chapters and more than 40 000 members.

On 18 May 2014, the University of Vermont in the USA will confer an honorary doctorate on Prof Jansen for his passionate leadership in higher education and his contributions as scholar to benefit students across the world.

In June 2013, Prof Jansen received the Education Africa Lifetime Achievement Award for Africa in New York at a joint function of Education Africa and Brand South Africa. He joined a list of recipients including Sir Bob Geldof, Sir Richard Branson and Archbishop Emeritus Desmond Tutu. The Education Africa Lifetime Achievement Award for Africa is a highly-regarded recognition on the world stage, awarded to individuals who focus the attention of the global community on the obstacles some of the poorest African nations face.

The University of California in the USA awarded him the Alice and Clifford Spendlove Prize in Social Justice, Diplomacy and Tolerance. The award is made in recognition of persons who exemplify in their work the delivery of social justice, diplomacy and tolerance in the diverse local and global society.

Also in the United States, Prof Jansen has been invited to be Messenger Lecturer for Fall 2013 at Cornell University. He will give three lectures and interact with the students and staff of Cornell at various functions.

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