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07 January 2018
Photo Charl Devenish
Dr Anneke van der Spoel van Dijk is invested in contributing
to the global effort of stopping TB by 2035.
The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB).
She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB).
Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.
Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”
Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”
As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.
Sought-after title warms heart doctor’s heart
2013-10-02
02 October 2013
Prof Stephen Brown was recently named as Ons Stad’s Bloemfonteiner of the Year, a title Prof Brown views as “one of the greatest moments” of his life.
Prof Brown, a cardiologist in the University of the Free State’s (UFS’) Department of Paediatrics and Child Health, has dedicated his life to children’s hearts ever since he qualified as paediatrician.
He is also involved in the teaching of under- and postgraduate students, as well as the training of doctors in paediatric cardiology. He is also jointly responsible for the planning and compilation of the undergraduate training programme for final-year students.
“This title is truly one of the greatest moments of my life. I feel humbled and impressed by the quality of the nominations for the title, which makes me feel small among the others.
“As physician I appreciate it even more, because this award means that the people of our wonderful city value the achievements and work of the doctors in our city – this warms my heart.”
Under Prof Brown’s leadership, Bloemfontein’s Paediatric Cardiology Unit is the only certified and recognised unit for pulmonary-valve implants in Africa.
The development of a local prenatal fetal heart screening and diagnostic programme, as well as adult congenital heart clinics, is due to his work and passion for his study field.
At the World Congress in 2013, he was involved as operator from South Africa in the first ‘direct telecast’ of children’s heart procedures.
“I hope that the award will help in our campaign to raise awareness in the community about children’s heart diseases. They are, after all, the people I work for."
The UFS also congratulates Sheri Brynard on her nomination for the title. Paul Colditz, the winner for 2012, is also a UFS Board member.