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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Distinguished Kovsie medical student bestowed with Abe Bailey Bursary
2013-10-14

14 October 2013

Residence head, SRC member, Golden Key International Honour Society member and now: Abe Bailey scholar as well. These are some of the achievements and leadership titles that Michael van Niekerk, a fourth-year MBChB student at our university, has under his belt.

One of 18 South Africans countrywide, Van Niekerk is to visit institutions in England and Scotland as a recipient of the prestigious Abe Bailey Travel Bursary for 2013. The scholarship acknowledges excellence in academics, leadership and community service and is awarded annually to third-year students and/or junior lecturers not older than 25 years of age.

The recipients of the 2013 Abe Bailey scholarship leave for Cape Town on 20 November 2013 to attend a two-day orientation process. Following this, they will then travel to London and Edinburgh, where they will visit universities, as well as places of interest such as London’s House of Lords.

Van Niekerk, who recently visited the USA as part of the Golden Key International Honour Society’s International Scholar Laureate programme, says it is an incredible honour to be this year’s Abe Bailey recipient for the UFS. "I am very blessed to not only excel in the medical field, but also in leadership and other aspects and I believe that this is absolutely grace from Above. I believe that this is an opportunity and a step to a better future. I don’t believe in being average and believe that this is an opportunity to prove myself and achieve more."

This Kovsie student says he has great plans for the future. "If it is God’s will, I would very much like to specialise in neurosurgery, cardiothoracic surgery or trauma surgery. I would like to be part of the Rhodes Scholarship and would strive to reach it."

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