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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Learning to serve, serving to learn
2013-10-18

 

At the Community Engagement Open Day were, at the back, from the left: Dr Choice Makhetha, Vice-Rector: External Relations; and Rev Billyboy Ramahlele, Director of Community Engagement. In front are, from the left: Selby Lengoabala, Betlehem Unit Manager; Councillor Job Tshabalala, Acting Executive Mayor; and Councillor Isaac Tshabalala, Strategic Manager in the office of the Executive Mayor of the Dihlabeng Local Municipality.
18 October 2013

The university held its first Community Engagement Open Day in order to honour outstanding individuals and highlight programmes that advance its civil responsibility. Hosted by the UFS Community Engagement Directorate, local community members, students and staff gathered in the Callie Human Centre at the Bloemfontein Campus, displaying what they do to empower communities.

Partners in Community Engagement (CE) and Service Learning (SL), local government, community-based research, student volunteer groups, Non-Profit Organisations (NPOs) and private business interacted with guests at their various information stalls. Faculties and departments displayed their distinctive programmes and demonstrated a renewed commitment to change lives through sharing knowledge, rendering services and fostering empowerment among communities.

In recognition of outstanding service, commitment and excellence in the field of community engagement and service learning, some staff members, researchers and some partners received the Vice-Rector’s Award for Community Engagement. Among them was Prof Matie Hoffman, who was honoured for his longstanding involvement in research at the Boyden Observatory. He is currently at the forefront of renovations for the planetarium at Naval Hill. In the category for external partners, REACH and Heidedal Childcare were awarded for demonstrating commitment towards their partnership with the university. The acting Executive Mayor, Job Tshabalala, also received an award on behalf of Dihlabeng Local Municipality Mayor, Tjhetane Mofokeng, for their involvement in education and social cohesion programmes. During his keynote address, the Director of Community Engagement, Rev Billyboy Ramahlele, emphasised the contribution that community engagement has on the two major strategic programmes of the university, namely the Academic and Human Projects. He pointed out that CE creates a platform on which students learn to appreciate human diversity in a real and unprotected set-up.

The interactions of the Open Day are expected to raise awareness, cultivate understanding among partners, encourage solid alliances and bring to the fore an acknowledgement of community engagement as the integral part of higher education.

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