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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Kovsie student trailblazing to literary stardom
2013-10-24

 

Ace Moloi with a copy of his book In Her Fall Rose a Nation
Photo: Jerry Mokoroane
24 October 2013

Ace Moloi proves that ambition and self-belief are key ingredients in achieving your dreams. At merely 21-years of age, this Kovsie student made his entrance onto the literary scene with the launch of his first novel. In Her Fall Rose a Nation tells the story of a young girl who leaves her rural home to further her studies in the city. Loosing herself in the excitement of student life, she gets kicked out of university. As a result she has to find refuge in the streets that devour her last bit of hope of rising again. The novel, published by New Voices Publishing, was introduced to an eager audience at the Bloemfontein Campus.

Moloi, a third-year Communications student and prime of House Tswelopele, says his book is a unique offering that will inspire and intrigue.

"The inspiration behind this project emanates mainly from the realisation that as much as we bemoan the lack of reading among young people – particularly in the townships and rural areas – we haven’t taken the initiative to write books that will speak to them and their day-to-day circumstances."

The talented writer, who is also a content contributor for News24 and a former IRAWA Post news editor, says he has been influenced by the writings of extraordinary individuals such as Kwasi Koranteng, Steve Biko and Dr KPD Maphalla. It took him three years to write the book, Ace says, mentioning that it first started as a Sesotho novel, that was later turned into English.

Already working on his second manuscript, Prey and Predators, Ace’s message to fellow students is to never underestimate the power of dreams. "By nature, dreams are unique, and so is yours. Own it up. Defend it. Realise it. Most importantly, never allow anyone to make you feel guilty for having great ambitions, for without ambition there is no meaning at all to life."

* In Her Fall Rose a Nation sells for R100 and can ordered from Ace at ace.moloi@gmail.com. The book can also be ordered online for R150 from New Voice Publishing online bookstore at www.newvoices.co.za.

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