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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS and DRC Free State sign cooperation agreement
2013-11-27

The University of the Free State (UFS) recently signed a cooperation agreement for a period of five years with the DRC Free State. In this contract it is agreed that the university will offer theological training to DRC ministers.

With this agreement, the DRC Free State confirmed that the theological training currently offered by the Faculty of Theology meets the requirements and expectations of the church in such a way that her ministers can be trained within this context and ethos of the UFS. The Faculty of Theology believes that church involvement in the training of students of the DRC FS (as with all other churches), as well as the spiritual formation and guidance of those students, are important during their training and should be retained.

According to Prof Driekie Hay, Vice-Rector: Academic, the Faculty of Theology at the UFS is the only institution in Central South Africa that offers complete and comprehensive theological training.

“As the youngest of the faculties at the UFS, this faculty has developed a lot in a relatively short time and is firmly established on many levels. The faculty currently offers training in all theological disciplines, from undergraduate to PhD level,” says Prof Hay.

The Faculty of Theology offers a unique national and international contribution to the development of the church, society and academic theological environment. This is made possible through quality theological training and specialist research based on a framework of classical theological training and research.

The new cooperation agreement that was signed acknowledges the uniqueness and independance of both the DRC in the Free State and the Faculty of Theology as public institutions, and strives to serve the interests of both institutions best.

According to Prof Fanie Snyman, acting Dean of the Faculty of Theology, this new agreement proves that the UFS is not only training students academically, but is also concerned with the human aspect of its students.

“It is a privilege for the university to be associated and work together with the DRC in this way,” says Prof Hay. Rev Jan Lubbe, Moderator of the DRC Free State, also indicated that he is very positive and excited about the new agreement.

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