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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

International scholars take part in 2nd Summer Programme
2013-11-28

 
Dr Gansen Pillay, Deputy Chief Executive Officer of the National Research Foundation, explaining to the scholars what will be expected of them.
Photo: Steven Collett

On Monday 25 November 2013, young researchers were welcomed to the University of the Free State (UFS) to take part in the 2nd Annual South African Young Scientists Summer Programme (SA-YSSP).

These 36 scholars, hand-picked from some of the world’s most promising and top researchers, will spend altogether three months in the Free State to work on various projects.

The SA-YSSP is a novel three-month programme for advanced doctoral candidates whose research interests align with the Department of Science and Technology’s (DST) grand challenges and the International Institute for Applied Systems Analysis’ (IIASA) current research programmes regarding global environmental, economic and social change.

Dr Priscilla Mensah, Co-director of the SA-YSSP, says the University of the Free State is proud to host the Southern African Young Scientists Summer Programme, which brings together some of the world's greatest minds in systems analysis to work with talented young scientists on addressing complex global challenges.

“At the end of the programme, the young scientists will showcase their work during a two-day colloquium (20-21 February 2014), which will also be streamed live to a wide audience. Additional information on the programme is available at www.ufs.ac.za/sa-yssp."

The programme will form part of an annual three-month education, academic training and research capacity-building programme jointly organised by IIASA, based in Austria, the National Research Foundation (NRF) and the DST. IIASA is an international research organisation that conducts policy-oriented scientific research in the three global problem areas of energy and climate change, food and water, and poverty and equity. South Africa’s engagements with IIASA, specifically with regard to the SA-YSSP, relate primarily to the DST’s Ten-Year Innovation Plan.

The UFS is the first institution outside Austria to host the Summer Programme. Researchers in the programme are, among others, from South Africa and the rest of the African continent, the USA, the Netherlands, India, Hungary, Austria and Germany.

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