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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Prof Dennis Francis delivers keynote address at colloquium on homophobia and transphobia
2013-11-29

Prof Dennis Francis
Prof Dennis Francis, Dean of the Faculty of Education, delivered the keynote address at a colloquium focusing on homophobia and transphobia in schools.

The UNESCO and Gay and Lesbian Memory in Action (GALA) is hosting Transforming Classrooms, Transforming Lives: Combating Homophobia and Transphobia in Education, at the University of Johannesburg.

Looking specifically at the Southern African context, this multi-disciplinary event builds on the highly successful 2012 Colloquium on Challenging Homophobia and Transphobia in South African Schools.

The colloquium allows educators, policy makers, researchers and activists from across Southern Africa to discuss the scope and impact of homophobia and transphobia in the education sector. It also creates a space for delegates to present new research, to discuss recent front-line activities, to reflect on good practices and to workshop future interventions.

Prof Francis’ paper on challenging heterosexism and heteronormativity in a South African school, was recently published in the South African Journal of Education.

For his research, Prof Francis looked at how learners understand and portray gay and lesbian characters and heterosexism by means of Participatory Theatre. He also did research on how teachers in South African schools position themselves on teaching about sexual diversity.

Prof Francis’ research papers also points out how schools promote compulsory heterosexuality and that homosexuality is something to be hidden and kept separate from teaching, learning and daily school life.

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