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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS launches a Small and Medium Enterprise (SME) Observatory, first of its kind in South Africa
2013-12-04

In cooperation with its partners, the Centre for Development Support at the University of the Free State (UFS), launched the SME Observatory at a function on the Bloemfontein Campus. This initiative is the first of its kind in South Africa. 
 
According to Willem Ellis, Director of the Centre for Development Support, this is a public-private partnership between the UFS, the International Labour Organisation (ILO) and the Department of Economic Development, Tourism and Environmental Affairs (detea), which aims to gather information for research on small and medium enterprises. “With this research we will endeavour to empower policy formulators to make the right decisions in terms of development on a local, provincial and national level,” Ellis said. 
 
Presentations and the panel discussion at the launch covered topics such as: 
  • How many enterprises can survive in a town?
  • Are entrepreneurs being set up for failure? 
  • Is SMEs the answer to the unemployment question? 
  • The cost of red tape: is SMEs being tied down? 

To demonstrate the applicability of the enterprise architect for issues relating to enterprise policy, as well as entrepreneurship strategies, it was decided to focus the pilot phase of the observatory on towns in the Free State. Dr Daan Toerien, research associate at the Centre for Development Support, and Johannes Wessels, Project Manager of the SME Observatory, compiled the report: “50 Towns in the Free State: What the Enterprise Architecture of these towns is telling us about Entrepreneurial Space.” 
 
In his presentation at the launch, Dr Toerien said: “The Enterprise Observatory’s prime goal is to present valuable facts and insights about enterprises in the domains it is observing.” He has developed a database that contains information on a large number of South African towns. He said that studying the enterprise architecture of towns will contribute significantly to inform the policy and strategy debate on LED and enterprise development. “These activities will add valuable data and insights to approach entrepreneurship in the Free State and, after the pilot phase, also in other provinces in South Africa. The Free State government, district and local municipalities, and the consultant fraternity serving them, should find the SME observatory’s activities of value,” he said. 
 
Wessels said that the SME Observatory of South Africa is dedicated to base its arguments on sound theory, science and applied research; to engage policy and decision makers on an evidence-based approach; operate in a politically non-aligned mode in order to mirror truthfully the impact of policies and decisions and to partner with policy makers, entrepreneurs, public administration, think tanks, research institutions, business representatives and NGOs on building networks and alliances to promote an open and competitive enterprise environment.

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