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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Standing ovation for the UFS Camerata in St Petersburg, Russia
2013-11-26

 
Jan Moritz Onken conducting the Camerata during their performance at the 13th International Conservatoire in St Petersburg, Russia.

The OSM CAMERATA (OSMC), flagship ensemble of the University of the Free State’s Odeion School of Music, received a standing ovation during a gala concert at the 13th International Conservatoire Festival presented on 7 November 2013 in the Glazunov Hall under the baton of Maestro Jan Moritz Onken.

The International Conservatory Festival was founded in 2001 by the St Petersburg Rimsky Korsakov Conservatory and has since then become an annual highlight on the concert calendar of St Petersburg.

For the last thirteen years, the festival has developed as a centre of excellence for artists, lecturers, and music experts who represent higher institutions of music from almost every continent. This forum has introduced more than 200 conservatories internationally, and literally produced hundreds of concerts, master’s classes and lectures. Internationally-acclaimed musicians such as Yuri Temirkanov, Rodion Shchedrin, Saulius Sondeckis, Krzysztof Penderecki, Valery Gergiev, Vasily Sinaisky and Semyon Bychkov, as well as young talented performers on the brink of their international careers, have participated in the festival over the years.

The OSMC presented the artistic director of the festival, Prof Lydia Volcheck, with audio-visual material as an audition and received a formal invitation from Prof Mikhail Gantvarg, Rector of the St Petersburg Rimsky Korsakov Conservatoire, in May 2013. Jan Moritz Onken (who was appointed as the OSMC chief conductor and artistic director for 2012) prepared the ensemble with vigour and discipline. Experienced international OSM alumni and several young international professionals served as mentors throughout the year preceding the event.

The OSMC gave two recitals during the festival – a gala performance in the Glazunov Hall, as well as a concert in the St Petersburg White Hall. For the first concert on 7 November (entitled FOUR CONTINENTS FESTIVAL), the OSMC shared the stage with a piano duo from the Karol Szymanowski Academy of Music (Katowice, Poland), the String Quartet of the Colburn Conservatory of Music (Los Angeles, USA), as well as an ensemble of Japanese Traditional Instruments from the Tokyo University of the Arts (Japan).

After the last reverberating notes of the performance of the Phantom Waltz (a work commissioned by the OSM from the South African composer Hendrik Hofmeyr), a thunderous applause and shouts of bravo exploded! The OSMC responded spontaneously with a kwela improvisation as an encore.

Dagbreek broadcast: http://bit.ly/1evTgR3

 

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