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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

University recognised as leading Higher Education Institution for students with disabilities
2013-12-05

The University of the Free State has been lauded for creating an inclusive environment for persons with disabilities, winning the 2013 National Disability Higher Education Institution Award. The award was presented at the National Disabilities Awards held in Port Elizabeth as part of the celebrations for International Day of People with Disabilities.

The Deputy Minister for Women, Children and People with Disabilities, Hendrietta Ipeleng Bogopane-Zulu, commended the university during the event for standing out among South African institutes of higher education. She told the audience the award gives recognition to institutions that demonstrate, through their strategy and policy, the provision of an inclusive environment for persons with disabilities. This is done through the use of technology and accessibility at their premises.

It's not the first time the university received praise from the deputy minister. In 2012 she visited the Bloemfontein Campus as part of a nation-wide roadshow to assess disability compliance and support services at all universities and FET colleges. Impressed with the work of the Unit for Students with Disabilities (USD), she recommended that staff from various higher education institutions visit the campus to gain insight into what they are doing.

Receiving the award on behalf of the university, Hetsie Veitch, Director of the USD, says the award recognises the commitment of the university’s senior leadership, who support the USD in creating a learning environment that is welcoming and accessible to all students.

Rudi Buys, Dean of Student Affairs, says the university is appreciative of what the USD does and says the award is a great achievement for a unit that only started functioning on its own three years ago. “The role of our support unit for Students with Disabilities has since 2010 grown to hold not only a prominent place in our institutional reflection on and implementation of approaches of universal access, but also to stand as leading department in building and bearing witness to the commitment of the UFS to values of universal access.”

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