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07 January 2018
Photo Charl Devenish
Dr Anneke van der Spoel van Dijk is invested in contributing
to the global effort of stopping TB by 2035.
The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB).
She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB).
Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.
Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”
Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”
As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.
An astrophysics pioneer at Kovsies
2014-01-05
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| Prof Pieter Meintjes |
Over the last decade Prof Pieter Meintjes’ strong background in astrophysics led to the development of a course of excellence at the University of the Free State.
Today we present an Astrophysics degree at our university, from first-year courses to PhDs.
Meintjes matriculated at the Sybrand van Niekerk High School in Sabie and completed a BSc in Physics and Mathematics at the North-West University in 1988. In 1990 and 1993 he respectively obtained his MSc and PhD in Physics from the same university.
Hereafter he spent a post-doctoral year at the Max Planck Institute for Space Science near München in Germany. In January 1997, Meintjes was appointed as a senior lecturer at our university’s Department of Physics. He was promoted to Professor in Physics in 2008.
Prof Meintjes is a member of the South African Institute for Physics (SAIP) and during 2002-2004 he was also co-chair of the astrophysics and space science group of SAIP. He serves on the executive committee of the National Astrophysics and Space Science Programme (NASSP) and is often a visiting lecturer at the University of Cape Town. He is a NRF-supported researcher and author and co-author of 70 publications in high-profile international journals and published conference issues.
During 2011-2013 he successfully delivered three PhD students along with one MSc student. His PhD students also delivered addresses at international conferences in Champery (Switzerland), Heidelberg (Germany), Paris (France), Barcelona (Spain) and Milan (Italy), Cape Town and the Kruger Game Reserve.
Over the last two years he has also been the author and co-author of six publications in Monthly Notices of the Royal Astronomical Society (MNRAS), as well as various publications in the Astrophysical Journal in support of the international planet search programme. A further 12 publications also came forth from Meintjes’ international conference contributions.
During the recent H.E.S.S. meeting in Namibia, Meintjes was appointed as the latest member of the highly-regarded international cooperation with H.E.S.S.
His membership of the H.E.S.S. group is due to his knowledge on gamma rays, which entails research on high-energy astrophysics.