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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

University welcomes new first-year students
2014-01-20

 

"Welcome to Kovsieland! The time of your life has just begun."

With these words Prof Jonathan Jansen, Vice-Chancellor and Rector, welcomed thousands of new first-year students. They attended a welcome ceremony with parents and guardians on the Bloemfontein Campus.

The arrival of first-year students saw the campus come to life, with the area in front of the Main Building turned into an open-air venue. A festive atmosphere prevailed, with live music filling the air and residences camping on the grass surrounding the area. Those who came out to welcome the new first-years, included members of the rectorate, the deans of all seven faculties and the student leadership.

"You are the smartest in the country," Prof Jansen told the new Kovsie students, informing them that thousands applied, but did not make it because of limited space. "We took the best students," he informed the large crowd, telling them that the more than 4 000 new Kovsies come from all over South Africa and the continent.

"This university is about high academic standards for its staff and its students. This is a place where we respect people, irrespective of where they come from, how they pray and how they love," Prof Jansen added.

Prof Jansen brought laugher to the audience, sharing tips for first-years from senior students, among them jewels like, "Wear flip-flops in the shower, you never know what the science students left behind" and "Don't keep your boyfriend back home, you never know what you will get at the university."

Phiwe Mathe, SRC President of the Bloemfontein Campus, added to the list of tips, telling first-years to have a hunger for knowledge and be open minded. "Participate in life on campus and ask important questions," he urged them. "There is plenty to learn at this university. "

Here is an idea where our students come from:
Eastern Cape: 395
Free State: 1701
Gauteng: 632
KwaZulu-Natal: 692
Limpopo: 333
Mpumalanga: 211
Northern Cape: 313
North-West Province: 243
Western Cape: 171

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