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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

New Research in Hebrew Language and Culture
2014-01-17

The newly formed Department of Hebrew at the university is hosting an international conference from 27 to 29 January 2014. The conference has speakers from Israel, the United States, Canada, the United Kingdom and Saudi Arabia, as well as South Africa, Zambia, Congo and Nigeria. The goal of the conference is to highlight recent research in Hebrew language and culture by bringing international scholarship to the university and by highlighting the importance of the African context as a conceptual space for research on Hebrew. The rich cultural heritage of Hebrew finds particular resonance in Africa through the Hebrew Bible (Old Testament).

Some highlights from the conference include new research on the use of the ancient Hebrew script by Jews in the Persian and Roman periods as a means to maintain their religious and ethnic identity in times of distress, linguistic research on metaphors in the Hebrew Bible (Old Testament), Jews and non-Jews in the Hebrew and Yiddish writings of the South African author Morris Hoffman, the development of a rabbinic prayer for rain in the land of Israel and in South Africa, pedagogical advances in teaching Hebrew in Africa, and translation of the Hebrew Bible (Old Testament) as a means of reshaping VaTsonga cultural identity. 

The study of ancient and modern Hebrew language and culture provides important insights into the complex cultural situation in modern Africa, generally, and South Africa, in particular. The use of language by minority religious and ethnic groups can provide a powerful force for identity in turbulent political realities. Religious texts can be re-contextualised to provide guidance in new cultural contexts or translated to enhance and empower local societies. 

Venue: CR Swart Auditorium 

For more information, contact Prof Cynthia Miller-Naudé, Head of the Department of Hebrew at millercl@ufs.ac.za
 
 

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