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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Before and After Hector
2014-03-05

 

Björn Krondorfer

The apartheid years. The Anglo-Boer War. Mix these two topics together and you are ensured of a vigorous debate.

This was exactly the result at the Centenary Complex Gallery recently. During a round-table discussion, Kovsie students analysed an artwork by Gerrit Hattingh entitled “Before and After Hector”. The artwork depicts the iconic photo of Hector Pieterson – taken during the 1976 Soweto Uprising – staged as an event in the Anglo-Boer War.

The artwork functioned as the focal point at an exhibition curated by Angela de Jesus.The exhibition formed part of the International Research Forum hosted by the UFS which explored the topic of Societies in the Aftermath of Mass Trauma and Violence.

The ensuing conversation did not disappoint. The photograph evoked a wide range of views and emotions as the students reflected on the historic image representing violent and painful events of our collective past. As the students robustly exchanged their opinions, they developed strategies to support the reconciliation process. The dialogue assisted these students in formulating ways to look back at our history and use this knowledge to carry our society past traumatic experiences.

Prof Pumla Gobodo-Madikizela, Senior Research Professor in the Office for Research on Trauma, Forgiveness and Reconciliation, was astounded at the level of insight and wisdom the students displayed. “I am pleased that our students came to join us around the table to discuss this portrait which is iconic globally; to engage and also give their own interpretations of what they know, and what they do not know about our historical past. The dialogue about the interweaving of the Hector Pieterson photograph with the story of black victims of the British concentration camps is one of the ways of exploring the views of the younger generation in the aftermath of mass trauma and violence in our collective history,” Prof Gobodo-Madikizela concluded at the end of the conversation.

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