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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Madelief Residence bursts into colour
2014-03-12

You’ll be forgiven for thinking that your eyes are deceiving you when turning into the main entrance to the Bloemfontein Campus. Yet, it is still the graceful old lady of a building called Madelief. This 50-year-old female residence has donned a sparkling new ‘dress’, brandishing a trendy new look.

After extensive renovations kicked off during October last year, the long-awaited revamp left residents and Kovsies astonished. The makeover transformed the building into a sparkling gem, glistening in the Free State sun. Luminescent contra-vision windows, a remodelled veranda and a new façade propel this residence into modernity. A unique twist to the use of the façade is that it is reflective during both the day and night. During the daytime, the light reflects towards the residence and during the night it mirrors the entrance of the university. This feature lends an innovative and vibrant impression to the residence’s appearance.

“I’m so happy for my residence. It’s now the hub of attraction – everyone wants to visit and come have a look. Thanks to our Residence Head, the constructors and designers who came up with this concept and Housing and Residence Affairs. We look 50 years younger indeed and more vibrant,” Mamnosi Tshabalala, a senior resident at Madelief, beamed.

In celebration of this new phase of their residence, students plunged into a festival of colour – power paint exploding into rainbows over anyone who came near. Top management that attended the celebration could not escape the excitement. Profs Jansen and Morgan, Dr Wahl, Mr Koetaan and Rudi Buys were swept into the good cheer, snapping photos and making fantastic memories.

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