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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

South African citizens are yearning for a good story to tell
2014-03-13

 
Dr Sethulego Matebesi
Photo: Sonia Small

The 20 Year Review is in essence a continuation of President Jacob Zuma’s State of the Nation Address and the ‘we have a good story to tell’ narrative. The report provides a glowing picture of successes achieved over the two decades. The successes highlighted include the basic human rights enjoyed by South Africans, a marked improvement in economic growth, and the provision of social services such as health care, education and housing. And as expected, the Review is dedicated to Nelson Mandela.

The major accomplishments were made through the strategic policies of the ruling African National Congress (ANC). For example, emphasis has been on improving the lives of South Africans through pro-poor economic interventions, in building social cohesion, investing in economic infrastructure, fighting HIV and AIDS and tuberculosis, which resulted in improved health outcomes.

Generally, the assertions about ‘accomplishments’ have been made against solid evidence and are thus not debatable. What overshadows the 20 Year Review, is the story that is not being told. This is the story of a political economy marred by rampant corruption, high levels of unemployment, declining accountability, and unresponsiveness. This untold story has become the hallmark of President Zuma’s tenure. Meanwhile, the average South African citizen is still yearning for ‘a good story to tell.’

For more political comment or to speak to Dr Matebesi, please call René-Jean van der Berg at +27(0)83 645 5940.

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