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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS hosts the 11th annual Registrars’ Imbizo
2014-03-14

 

The University of the Free State recently hosted the 11thAnnual Registrars’ Imbizo which took place on 3 – 5 March 2014 at the Centenary Complex on the Bloemfontein Campus. Convening from across the country, up to 37 delegates affiliated to the Office of the Registrar shared their experiences and expertise. It also provided an opportunity to raise their concerns about their role in governance and academic administration.

At the opening of the Imbizo, Prof Driekie Hay, Vice-Rector: Academic Affairs, acknowledged the challenging and complex task of registrars in South African universities. Prof Hay highlighted the complexities in the history of higher education and the policy environment in particular. She raised concerns around funding for higher education, policy amendments passed through parliament and the newly-proposed reporting regulations for universities. She also referred to the introduction of a transformation oversight committee to evaluate the effectiveness of transformation at universities.

During the three-day Imbizo, delegates focused on matters such as finance and administrations, policy in higher education as well as social media and its impact on higher education. Dr Derek Swemmer, Registrar of the UFS and Chairperson, concluded the event. The visit included some sight-seeing – touring the Bloemfontein Campus and surrounds.

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