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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS blows the whistle on crime
2014-03-28


At the event were, from the left: Refiloe Seane, Director: Student Counselling and Development; Anastasia Sehlabo, SRC member for Accessibility and Student Support. Back, from the left: Melissa Barnaschone, Student Counselling and Development; and Mokgawa Kobe, Director: Protection Services.
Photo: Leonie Bolleurs

First-year students receive 1 000 whistles in project to combat crime.

Numerous safety measures were implemented by the University of the Free State in the past five years to ensure the safety of all the students and staff on all three campuses of the UFS. A large area of the UFS Campus is covered by security cameras. Red poles, equipped with panic buttons that can be activated to call for help, were also erected across the campuses.

At the beginning of 2013, as a further safety measure, whistles were handed out to female students in residences.

At an event on 26 March 2014, Refiloe Seane, Director: Student Counselling and Development, together with her team, handed over 1 000 whistles to the Student Representative Council to be distributed to first-year students. The whistles were sponsored by Prof Nicky Morgan, Vice-Rector: Operations and Mokgawa Kobe, Director: Protection Services.

“Female students are encouraged to use the whistles to call for help when they feel unsafe or are in danger. The objective is, firstly, to discourage criminals without suffering any negative consequences, and secondly, to get the attention of security or any other form of assistance,” said Melissa Barnaschone, Student Counselling and Development.

At the event, Mokgawa said: “The moment you blow this whistle, you say to the potential criminal:

  • I hate what you do
  • I will not keep quiet about it
  • I am doing something against crime.”

 

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