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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Kovsies present case studies to Tata Africa
2014-04-15

Tata Africa welcomed four top scholarship winners from the University of the Free State’s (UFS’s) Business Management Department who were awarded academic bursaries in 2013 for developing practical marketing strategies for the Tata group companies as part of their studies.

The students presented their winning case studies to a panel of Tata Africa executives and senior managers in Johannesburg.

“The Tata group places social responsibility at the core of its business DNA. This kind of support characterises our commitment to communities where Tata companies operate worldwide,” said Thami Mbele, Managing Director for Tata Africa Holdings.

“The impressive work of the Strategic Marketing students of the University of the Free State’s Business Management Department, who have been using Tata group companies as examples for their practical marketing strategies, deserve recognition,” he added.

To date, Tata has invested R275 000 in the University of the Free State’s talent pool. Over the past six years, Tata Africa has invested over R10 million in scholarships in Africa.

Second-semester students of the Strategic Marketing course, Lebohang Masoabi, Estie Brown, Lynne Harvey and Cecile Boshoff, were given a rare opportunity to apply their theoretical knowledge by developing practical marketing strategies for Tata group companies operating in Africa. Students presented their ideas to a panel of UFS and Tata representatives in 2013, and 27 out of 78 groups were selected to compete for academic bursaries sponsored by Tata.

Through its scholarship programme, Tata Africa is committed to investing in future African entrepreneurs, leaders of industry and business.

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