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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

SRC and Kovsies stand against abuse
2014-04-15

The SRC took the lead on Monday by orchestrating a campaign to create awareness and instill consciousness on campuses to act against the abuse of women and children.

During a march from the Thakaneng Bridge to the Main Building on the Bloemfontein Campus, the SRC led students in a Pledge Against Women and Children Abuse to ensure that the UFS community become accountable. The message proclaimed, was one of zero tolerance for the abuse of women and children.

The Dean of Student Affairs, Rudi Buys, addressed students, saying: “No more. This cannot be just another march, but something to speak directly to injustice.”

This campaign was aimed at ensuring that relevant information and services are provided to help women and children. Representatives of Health and Wellness, psychologists and social workers, as well as representatives from the Centre of Trauma Forgiveness and Reconciliation, the Centre for Safety and Security and the Institute of Race and Reconciliation were present during this campaign.
The Vice-Rector: External Relations, Dr Choice Makheta, stressed the point of women and children’s wellbeing, by saying: “As a university we must make sure women are treated well… that children are treated very well.”

Violence against women and children in South Africa happens regardless of age, class or colour. Studies shows 50% of women have been reported experiencing violence at the hands of their intimate partners. Local studies also show that 28% of men have admitted to being rapists. Every hour a child is abused in South Africa.

But Kovsies say “No more! No more!”

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