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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Kovsie archer aims for 2016 Olympics
2014-04-24


Sariça Coetzee

For some of us, archery is just something we see on film and television, like in the Hunger Games movies or on the Arrow TV series. Sariça Coetzee, a first-year BA Psychology and Criminology student, however, is almost like South Africa’s very own Katniss Everdeen.

Sariça recently won two gold medals in the division for Junior Women at the South African National Archery Association’s (SANAA’s) National Archery Championships. With the qualifying heats taking place next year, the Olympic Games of 2016, which is just around the corner, is beckoning her.

“I am working hard to get there and would love to go,” says Sariça.

“I train on a regular basis with Riaan Schoeman from Kovsies’ Exercise and Sport Sciences, in order to improve my technique and strength.”

Sariça’s training includes shooting at targets and spending time in the gym.

“I spend about three hours per day, four days a week, on training. In archery it is crucial to be able to keep your body stable when the wind is blowing.”

Sariça, who matriculated at Sentraal High School in Bloemfontein, stared with archery seven years ago.

“We drove past Old Grey’s archery club and I just wanted to do it as well,” she says.

“I begged my parents for almost a year to let me do it. They thought it was just a passing fancy, but I really developed a passion for the sport and had a feeling for archery from the beginning.”

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