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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

These boots are made for walking ... to Cape Town
2014-04-24

On Thursday 1 May 2014, four pairs of feet gave their first stride on a journey that will last for 33 days and stretch over 1 000 kilometres.

These feet belong to four very brave volunteers who will walk all the way to the Cape in order to highlight the problem of food insecurity among students.

Adéle van Aswegen and Ntokozo Nkabinde from the University of the Free State (UFS), together with Ronél Warner and Nico Piedt, both from Bloemfontein, are undertaking this hike as part of a fund-raising effort for the UFS’s No Student Hungry bursary (NSH bursary).

The NSH bursary, established in 2011 by Prof Jonathan Jansen, the UFS’s Vice-Chancellor and Rector, and Rudi Buys, Dean of Student Affairs, is aimed at alleviating food insecurity among students at the UFS.

The food bursary is awarded on the grounds of financial need, good academic performance, active participation in student-life programmes and a commitment to community service.

“The NSH bursary of about R30 per student forms only a small part of a student’s day, but it makes a huge difference in their lives,” says Vicky Simpson, coordinator of this programme offering assistance to more than 100 students.

You can follow our hikers’ progress on Twitter by using the #NSHstride. We will also keep you updated on Facebook and our website.

Meanwhile, everyone is invited to show their support for the hikers in a fun way. Take a picture of your foot (or feet), tweet the photo with #NSHstride @UFSweb or post it on your Facebook page and challenge all your friends to do the same.

Daily updates:
(You can also follow us on @UFSweb for daily tweets)

Day 14: 14 May 2014
18:33
43 km
Joalani Guest Farm

Day 13: 13 May 2014
17:30
33 km
Die Rondawels

Day 12: 12 May 2014
16:49
40 km
Aandrus B&B in Richmond

Day 11: 11 May 2014
39 km
Wortelfontein (Magdel and Christiaan)

Day 10: 10 May 2014
15:44
34 km
Hanover Lodge

Day 9: 09 May 2014
40.8 km
Camping between Colesberg and Hanover

Day 8: 08 May 2014
15:25
33.7 km
Colesberg, The Lighthouse Guesthouse

Day 7: 07 May 2014
15:08
23 km
Orange River Lodge

Day 6: 06 May 2014
15:57
51.06 km
Gariep Forever Resort

Day 5: 05 May 2014
12:18
28 km
Rondefontein

Day 4: 04 May 2014
15:27
35 km
Trompsburg: Fox Den

Day 3: 03 May 2014
17:30
46.74 km
Edenburg Country Lodge (Hotel)

Day 2: 02 May 2014
11:44 am
15.3 km
Tom's Place

Day 1: 01 May 2014
32 km
Leeuwberg

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