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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Internet Broadcast Project wins international award
2014-05-05

The Enterprise Video Awards (EVA) named Kovsies’ Internet Broadcast Project (IBP) the winner of the Innovation in Pedagogy category. During a glitzy ceremony on 28 April 2014 in Madison, USA, Edward Musgrave, Deputy Director of the ICTISE Division, took to the stage to receive the award.

The IBP makes use of the best teachers in the Free State to broadcast lessons on more than ten subjects to school learners who do not have access to quality education. And it is not only the learners who benefit. Their teachers receive invaluable training in the process as well.

This remarkable programme provided the judges with plentiful evidence to be named the winner. The IBP team had to come up with highly innovative solutions to overcome the costs of local bandwidth constraints. The result? High definition videos being streamed in real time across a 1Meg line. Simultaneously to 70 centres across the Free State. Added to that is the fact that multiple images are broadcast as one, reaching 43 000 learners and 1 250 teachers per week. To top it all, the broadcast is interactive – the learners can ask questions directly to the teacher during the lesson.

All of this at no cost to the schools.

“It is remarkable for a South African university to receive this international recognition,” said Sarietjie Musgrave, heading up the ICTISE programme at the South Campus. “It raises awareness, not only for the work we do, but also the community work the university does,” she said.

And now the Free State has the highest pass rate of matriculants in South Africa.

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