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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Now prospective Kovsies also know the feeling
2014-05-12

 The UFS was a hive of excitement and activity with the annual Kovsie Open Day on Saturday 10 May 2014.

From drumming up a storm during the welcoming ceremony to moving about the lively students and vibrant residence stalls, prospective students and parents can now also say that ‘only a Kovsie knows the feeling’. Visitors also had first-hand experience of how accessible our Vice-Chancellor and Rector, Prof Jonathan Jansen, really is. At the Talk to Me gazebo outside his office, Prof Jansen dished up food while having a chat with parents.

This gesture echoed what Prof Jansen said earlier the morning as he addressed visitors to our Bloemfontein Campus in the Callie Human Centre. “The difference between us as Kovsies and other universities is that we are interested in you as a human being,” he said.

He then went on to introduce some of Kovsies’ top achievers. Among others were Izelle Lategan (U/21 SA women’s hockey player of 2013), Wayde van Niekerk (SA and Varsity Athletics 400m champion) and Izelke Klindt (BSc Hons in Astro Physics and winner of the Dean’s Medal in the Faculty of Natural and Agricultural Sciences for 2014).

OFM presenter Success Lekabe, who acted as programme leader during the welcoming ceremony, praised the UFS as one of “the best university institutions from across South Africa.”

“Kovsies are changing their students’ lives to change the lives of others,” Lekabe said.

The 2014 Kovsie Open Day, with all its fun and laughter, reflected the truth of the UFS as an academic institution that inspires excellence and transforms lives to all its visitors.

Even if you missed the Kovsie Open Day, be sure to grab the chance to study at our university and ensure a lifetime of excellence and innovation.

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